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Friday, September 7, 2018

Dna Consultants Confirms African origin for Ancient Egyptians ...
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The genetic history of Egypt's demographics reflects its geographical location at the crossroads of several major biocultural areas: North Africa, the Sahara, the Middle East, the Mediterranean and Sub-Saharan Africa.


Video DNA history of Egypt



Ancient DNA

Contamination from handling and intrusion from microbes create obstacles to the recovery of ancient DNA. Consequently, most DNA studies have been carried out on modern Egyptian populations with the intent of learning about the influences of historical migrations on the population of Egypt. A study published in 1993 was performed on ancient mummies of the 12th Dynasty, which identified multiple lines of descent.

In 2013, Khairat et al. conducted the first genetic study utilizing next-generation sequencing to ascertain the ancestral lineage of an Ancient Egyptian individual. The researchers extracted DNA from the heads of five Egyptian mummies that were housed at the institution. All the specimens were dated to between 806 BCE and 124 CE, a timeframe corresponding with the Late Dynastic and Ptolemaic periods. The researchers observed that one of the mummified individuals likely belonged to the mtDNA haplogroup I2, a maternal clade that is believed to have originated in Western Asia.

A study published in 2017 described the extraction and analysis of DNA from 151 mummified ancient Egyptian individuals, whose remains were recovered from Abusir el-Meleq in Middle Egypt. Obtaining well-preserved, uncontaminated DNA from mummies has been a problem for the field of archaeogenetics and these samples provided "the first reliable data set obtained from ancient Egyptians using high-throughput DNA sequencing methods". The specimens were living in a period stretching from the late New Kingdom to the Roman era (1388 BCE-426 CE). Complete mitochondrial DNA (mtDNA) sequences were obtained for 90 of the mummies and were compared with each other and with several other ancient and modern datasets. The scientists found that the ancient Egyptian individuals in their own dataset possessed highly similar mitochondrial profiles throughout the examined period. Modern Egyptians generally shared this maternal haplogroup pattern, but also carried more Sub-Saharan African clades. However, analysis of the mummies' mtDNA haplogroups found that they shared greater mitochondrial affinities with modern populations from the Near East and the Levant compared to modern Egyptians. Additionally, three of the ancient Egyptian individuals were analysed for Y-DNA, and were observed to bear paternal lineages that are common in both the Middle East and North Africa. The researchers cautioned that the affinities of the examined ancient Egyptian specimens may not be representative of those of all ancient Egyptians since they were from a single archaeological site.

Blood typing and ancient DNA sampling on Egyptian mummies is scant. However, blood typing of Dynastic period mummies found their ABO frequencies to be most similar to that of modern Egyptians.


Maps DNA history of Egypt


DNA studies on modern Egyptians

Genetic analysis of modern Egyptians reveals that they have paternal lineages common to other indigenous Afroasiatic-speaking populations in Maghreb and Horn of Africa, and to Middle Eastern peoples, these lineages would have spread during the Neolithic and were maintained by the predynastic period.

A study by Krings et al. (1999) on mitochondrial DNA clines along the Nile Valley found that a Eurasian cline runs from Northern Egypt to Southern Sudan and a Sub-Saharan cline from Southern Sudan to Northern Egypt.

Luis et al. (2004) found that the male haplogroups in a sample of 147 Egyptians were E1b1b (36.1%, predominantly E-M78), J (32.0%), G (8.8%), T(8.2%), and R (7.5%). E1b1b and its subclades are characteristic of some Afro-Asiatic speakers and are believed to have originated in either the Middle East, North Africa, or the Horn of Africa. Cruciani et al. (2007) suggests that E-M78, E1b1b predominant subclade in Egypt, originated in "Northeastern Africa", which in the study refers specifically to Egypt and Libya

Other studies have shown that modern Egyptians have genetic affinities primarily with populations of Asia, North and Horn of Africa, and to a lesser extent Middle Eastern and European populations.

Some genetic studies done on modern Egyptians suggest a more distant relationship to Sub Saharan Africans. and a closer link to other North Africans. In addition, some studies suggest lesser ties with populations in the Middle East, as well as some groups in southern Europe. A 2004 mtDNA study of upper Egyptians from Gurna found a genetic ancestral heritage to modern Northeast Africans, characterized by a high M1 haplotype frequency and a comparatively low L1 and L2 macrohaplogroup frequency of 20.6%. Another study links Egyptians in general with people from modern Eritrea and Ethiopia. Though there has been much debate of the origins of haplogroup M1 a recent 2007 study had concluded that M1 has West Asia origins not a Sub Saharan African origin Origin A 2003 Y chromosome study was performed by Lucotte on modern Egyptians, with haplotypes V, XI, and IV being most common. Haplotype V is common in Berbers and has a low frequency outside North Africa. Haplotypes V, XI, and IV are all predominantly North African/Horn of African haplotypes, and they are far more dominant in Egyptians than in Middle Eastern or European groups.

Y-DNA haplogroups

A study using the Y-chromosome of modern Egyptian males found similar results, namely that North East African haplogroups are predominant in the South but the predominant haplogroups in the North are characteristic of North African and West Eurasian populations.

Distribution of E1b1b1a (E-M78) and its subclades

Autosomal DNA

Genomic analysis has found that Berber and other Maghreb communities are defined by a shared ancestral component. This Maghrebi element peaks among Tunisian Berbers. It is related to the Coptic ancestral component (see Copts), having diverged from these and other West Eurasian-affiliated components prior to the Holocene.

North Moroccans as well as Libyans and Egyptians carry higher proportions of European and Middle Eastern ancestral components, respectively, whereas Tunisian Berbers and Saharawi are those populations with the highest autochthonous North African component.

Copts

According to Y-DNA analysis by Hassan et al. (2008), around 45% of Copts in Sudan carry the haplogroup J. The remainder mainly belong to the E1b1b clade (21%). Both paternal lineages are common among other local Afroasiatic-speaking populations (Beja, Ethiopians, Sudanese Arabs), as well as many Nubians. E1b1b/E3b reaches its highest frequencies among Berbers and Somalis. The next most common haplogroups borne by Copts are the Western European-linked R1b clade (15%), as well as the archaic African B lineage (15%).

Maternally, Hassan (2009) found that Copts in Sudan exclusively carry various descendants of the macrohaplogroup N. This mtDNA clade is likewise closely associated with local Afroasiatic-speaking populations, including Berbers and Ethiopid peoples. Of the N derivatives borne by Copts, U6 is most frequent (28%), followed by the haplogroup T (17%).

A 2015 study by Dobon et al. identified an ancestral autosomal component of West Eurasian origin that is common to many modern Afroasiatic-speaking populations in Northeast Africa. Known as the Coptic component, it peaks among Egyptian Copts who settled in Sudan over the past two centuries. Copts also formed a separated group in PCA, a close outlier to other Egyptians, Afroasiatic-speaking Northeast Africans and Middle East populations. The Coptic component evolved out of a main Northeast African and Middle Eastern ancestral component that is shared by other Egyptians and also found at high frequencies among other Afroasiatic-speaking populations in Northeast Africa (~70%). The scientists suggest that this points to a common origin for the general population of Egypt. They also associate the Coptic component with Ancient Egyptian ancestry, without the later Arabian influence that is present among other Egyptians.


Ancient DNA reveals role of Near East and Egypt in cat domestication
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See also

  • Egyptians
  • Archaeogenetics of the Near East
  • Demographics of Egypt
  • Genetic history of North Africa
  • Ancient Egyptian race controversy
  • Population history of Egypt

DNA discovery reveals genetic history - CNN Video
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References

Source of article : Wikipedia